Past Events

Dr. Kwanghun Chung

Towards holistic imaging and phenotyping of intact biological systems

December 14, 2017 12:00 pm - 1:00 pm

Neurological Institute Alumni Auditorium

Holistic measurement of diverse functional, anatomical, and molecular traits that span multiple levels, from molecules to cells to an entire system, remains a major challenge in biology. In this talk, I will introduce a series of technologies including CLARITY, SWITCH, MAP (Magnified Analysis of Proteome), and stochastic electrotransport that enable proteomic and structural imaging for scalable, integrated, high-dimensional phenotyping of both animal tissues and human clinical samples. SWITCH enables over twenty rounds of relabeling of a single tissue with precise co-registration of multiple datasets by synchronizing key chemical reactions in tissue processing. With SWITCH, we demonstrated combinatorial protein expression profiling and high-dimensional quantitative analysis of the human cortex. MAP enables scalable superresolution proteomic imaging of large scale tissues by expanding intact organs four fold linearly while preserving their 3D proteome, nanoscopic architecture, and intercellular connectivity. Using MAP, we demonstrated molecular imaging of subcellular architectures and accurate tracing of densely packed neural projections. To speed up the labeling process in CLARITY, SWITCH, and MAP, we developed a novel electrokinetic method termed stochastic electrotransport, which enables immunolabeling of whole mouse brains within 1-3 days. We hope these new technologies to accelerate the phase of discovery in a broad range of biomedical research.

Graduate Student Research in Progress Talks

Presenters: Neeli Mishra and Sebi Rolotti

December 11, 2017 5:00 pm - 6:00 pm

HHSC 5th floor Conference Room

Dr. Greg DeAngelis

Neural Mechanisms for Perceiving Object Motion During Self-Motion

December 7, 2017 12:00 pm - 1:00 pm

Neurological Institute Alumni Auditorium

Andrew Fielding Huxley: Channels, Effectors and Imaging

A Symposium in Honor of the Centenary of Andrew Fielding Huxley

December 5, 2017 9:00 am - 6:00 pm

Caspary Audiorium, The Rockefeller University, 1230 York Ave., New York NY 10065

Sponsored by: The Shelby White and Leon Levy Center for Mind, Brain and Behavior; The Center for Neural Science and the Neuroscience Institute at New York University; The Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University.

Dr. Guoping Feng

Thalamic Reticular Nucleus Dysfunction in Neurodevelopmental Disorders

November 30, 2017 12:00 pm - 1:00 pm

Neurological Institute Alumni Auditorium

The Thirty-Ninth Annual W. Alden Spencer Award and Lecture

Dr. Ardem Patapoutian, The Scripps Research Institute and Dr. David Ginty, Harvard Medical School and HHMI Investigator

November 28, 2017 5:00 pm - 6:30 pm

Vagelos Educational Center, Room 201, 104 Haven Avenue

Graduate Student Research in Progress Talks

Presenters: Melissa Lee and Rebecca Rabinovich

November 20, 2017 5:00 pm - 6:00 pm

HHSC 5th Floor Conference Room

Grace Lindsay

Modeling the Impact of Internal State on Sensory Processing

November 20, 2017 12:00 pm - 1:00 pm

Jerome L. Greene Science Center, Lecture Hall, L9-065, 3227 Broadway, New York

Thesis Defense Seminar

Dr. Surya Ganguli

Emergent elasticity in the neural code for space

November 16, 2017 12:00 pm - 1:00 pm

Neurological Institute Alumni Auditorium

Society For Neuroscience 2017

November 11, 2017 8:00 am - November 15, 2017 12:00 am

Walter E. Washington Convention Center, 801 Mt. Vernon Place NW, Washington, DC 20001