Mechano-sensitive channels in sensory physiology and neural regeneration

Thursday, May 10, 2018 - 12:00pm to 1:00pm
Neurological Institute Alumni Auditorium
Among our senses, mechanical-sensing is the least well understood in part due to the difficulties in identifying and studying mechanical-sensitive channels that mediate the fist step of mechano-sensing. A group of Drosophila sensory neurons known as dendritic arborization (da) neurons have been used extensively for studying dendrite morphogenesis. It turns out that all da neurons are mechanical-sensitve and they are well suited for studying mechanical-sensitive channels such as Piezo, NompC and TMC. I will discuss our recent progress in this research area. There is also increasing evidence that mechano-sensitive channels play significant roles in several developmental processes. I will talk about their roles in axon/dendrite regeneration.
Dr. Yuh Nung Jan
Home Institution: 
University of California, San Francisco
Event Types: 
Neurobiology Seminars