Joriene C. De Nooij, Ph.D.
Research Interest
- PhD, 1998 Utrecht University (Netherlands)
July 2006 - February 2017 Associate Research Scientist, Department of Biochemistry and Molecular Biophysics, Columbia University.
May 1999 - June 2006 Postdoctoral Scholar, Department of Biochemistry and Molecular Biophysics, Columbia University.
Society for Neuroscience
2015-2017 TFFI Innovation award (together with Hynek Wicherle, Joachim Scholz, Ellen Lumpkin)
2000-2003 Fellow of the Helen Hay Whitney Foundation.
Woo, S.-H., Lukacs, V., de Nooij, J.C., Zaytseva, D., Criddle, C.R., Francisco, A., Jessell, T.M., Wilkinson, K.A., and Patapoutian, A. Piezo2 is the principal mechanotransduction channel for proprioception. Nat Neurosci. 18:1756-1762, 2015.
De Nooij, J.C., Simon, C.M., Simon, A., Doobar, S., Steel, K.P., Banks, R.W., Mentis, G.Z., Bewick, G.S., and Jessell, T.M. The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors. J. Neurosc., 35: 3073-3084, 2015.
De Nooij, J.C., Doobar, S., and Jessell, T.M. Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets. Neuron 77:1055-1068, 2013.
Chen, A.I., de Nooij, J.C., and Jessell, T.M. Graded activity of transcription factor Runx3 specifies the laminar termination pattern of sensory axons in the developing spinal cord. Neuron 49: 395-408, 2006.
Kramer, I., Sigrist, M., de Nooij, J.C., Taniuchi, I., Jessell, T.M., and Arber, S. A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification. Neuron 49: 379-393, 2006.
Chen, C.L., Broom, D.C., Liu, Y., de Nooij, J.C., Li, Z., Cen , C., Samad, O.A., Jessell, T.M., Woolf, C.J., and Ma, Q. Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron 49: 365-377, 2006.
For a complete list of publications, please visit PubMed.gov
- Sensory neuron specification and differentiation
- Proprioception
- Peripheral neuropathy/Disease modeling